D&P Globalchemical co.,ltd

pharmaceutical inter(2)

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co-1686
Specification: 1g 5g 10g
Detail: CO-1686 is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the IC50 values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively.

rucaparib
Specification: 1g 5g 10g
Detail: Rucaparib is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, and also shows binding affinity to eight other PARP domains.

abt-199
Specification: 1g 5g 10g
Detail: ABT-199 is a highly potent, orally bioavailable and Bcl-2-selective inhibitor with Ki of <0.01 nM.

pf-06282999
Specification: 1g 5g 10g
Detail: PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potential useful for the treatment of cardiovascular diseases.


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